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Genome-wide transcriptional and epigenomic map of primary and metastatic Sonic Hedgehog subgroup medulloblastomas

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NIAID Data Ecosystem2026-05-17 收录
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We report findings that illuminate a dynamic metastasis pathway in the common pediatric brain tumor medulloblastoma. Overall design: We examined binding states of H3K27ac and ATOH1 in primary and metastatic medulloblastoma driven by ATOH1 in collaboration with aberrant Sonic Hedgehog (SHH) signaling.

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2017-09-17
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