Crystal structure of JAK2 JH1 with type II inhibitor YLIU-04-105-1
收藏Protein Data Bank Japan2023-10-25 更新2026-03-28 收录
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Crystal structure of JAK2 JH1 with type II inhibitor YLIU-04-105-1 Descriptor: 3-{(4S)-2-[(cyclopropanecarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}-N-{3-[(4-ethylpiperazin-1-yl)methyl]-5-(trifluoromethyl)phenyl}-4-methylbenzamide, GLYCEROL, Tyrosine-protein kinase JAK2 Authors: Hubbard, S.R. Deposit date: 2022-01-05 Release date: 2023-06-21 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.45 Å) Cite: New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation. Cell Chem Biol, 30, 2023
创建时间：
2022-01-05
