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Yeast 20S proteasome with human beta1i (1-51) in complex with epoxyketone inhibitor LU-001i

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Protein Data Bank Japan2026-01-28 更新2026-05-24 收录
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Yeast 20S proteasome with human beta1i (1-51) in complex with epoxyketone inhibitor LU-001i Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... Authors: Maurits, E, Huber, E.M, Dekker, P.M, Wang, X, Heinemeyer, W, Florea, B.I, Groll, M, Overkleeft, H.S. Deposit date: 2024-06-21 Release date: 2024-07-17 Last modified: 2026-01-28 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structure-Based Design of Pan-Selective Peptide Epoxyketones for the Three Human Immunoproteasome Active Sites. J.Med.Chem., 69, 2026

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2024-06-21
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