Capsaicin evokes mechanical hypersensitivity in both wildtype and <i>Nf1^+/−</i> mice.

EF50 and 95% confidence limits (g) of force–response curves for the ipsilateral hindpaw before and 15 min after intraplantar injection of 0.001% capsaicin or vehicle. Curves were fit by non–linear regression with minimum constrained to 0 and maximum to 100. Numbers of mice in each group appear in brackets. *P<0.05, ** P<0.01 compared to vehicle at corresponding time point. †P<0.05, ‡P<0.01 compared to baseline value. aP<0.05 compared to WT at corresponding time point. Capsaicin evokes mechanical hypersensitivity in both wildtype and Nf1+/− mice.