During early postnatal life, extensive changes in gene expression occur concomitantly in multiple major organs, indicating the existence of a common core developmental genetic program. This program in
CTCF is an 11-zinc-finger DNA-binding protein that acts as a transcriptional repressor and insulator, as well as an architectural protein required for 3D genome folding. CTCF mediates long-range chrom
Transcriptome sequencing results of epididymal adipose tissue from mice on a high-fat diet supplemented with nuciferine and mice on a high-fat diet without nuciferine. To investigate the effect of nuc
Generation of widely differing and specialized cell types from a single totipotent zygote involves large-scale transcriptional changes and chromatin reorganization. Pioneer transcription factors play
