Evidence for toxic CAG trinucleotide repeats contributing to Huntington's disease though RNA interference
收藏NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP372507
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Mutant huntingtin CAG trinucleotide repeat mimetic hairpins are loaded into the RISC and kill cells through RNAi Overall design: NB7 cells were transfected with different HP mimicking two different mHTT variants or CAG contorl siRNAs. Subsequently, Ago protein associated short RNAs were pulled down using a GW182 peptide and subjected to smRNA Seq
创建时间:
2023-01-26



