Additional file 1 of Associations of visceral adipose tissue with bone mineral density and fracture: observational and Mendelian randomization studies

Additional file 1: Table 1. Baseline characteristics of the final application datasets by quartiles of VAT^ mass. Table 2. Baseline characteristics of the final application datasets by sex. Table 3. ICD-10 codes for fracture definition in the UK biobank. Table 4. Associations of VAT^ with heel BMD in men and women by BMI categories. Table 5. Associations of VAT^ with heel BMD in men and women by BMI categories after excluding participants with T2D, CVD or cancer at baseline. Table 6. Association of DXA-derived VAT mass with DXA-derived BMD among participants by BMI categories. Table 7. Associations of VAT^ with incident fractures in men and women by BMI categories. Table 8. Associations of VAT^ with incident fractures in men and women by BMI categories after excluding participants with T2D, CVD or cancer at baseline. Table 9. Schoenfeld residuals test of the Cox models. Table 10. Genetic variants associated with VAT^ in the UK Biobank. Table 11. MR estimates of the causal effects of VAT^ on DXA-derived BMD without excluding LM-associated SNPs. Table 12. MR estimates of the causal effects of VAT^ on fractures without excluding LM-associated SNPs. Table 13. MR Egger test of directional horizontal pleiotropy.