1—Was the study described as randomized?2—Was the method of randomization described and appropriate?3—Was the study described as double blind?4—Was the method of blinding described and appropriate?5—W
OBJECTIVES: To assess the methodological quality of intention to treat analysis as reported in randomised controlled trials in four large medical journals. DESIGN: Survey of all reports of randomised
BackgroundSystematic reviews of treatment interventions in stable or chronic conditions often require the synthesis of clinical trials with a cross-over design. Previous work has indicated that method
