Compressed files for densities for RNA strands, RISC molecules, and RISC-target complexes computed from Equ. (3) in paper entitled "Non-catalytic RISCs and kinetics determine mammalian siRNA sub-cell
Reactions were performed using an excess of RISC over substrate RNA in order to ensure single-turnover conditions. The initial rate of reaction was determined using data from the first 120 s. Filled c
aPearson correlation coefficient of siRNAs (total of 101) having a ΔG threshold ≥−34.6 kcal/mol with dataset B.bPearson correlation coefficient of siRNAs (total of 318) having a ΔG threshold
Compressed files for densities for RNA strands, RISC molecules, and RISC-target complexes computed from Equ. (3) in paper entitled "Non-catalytic RISCs and kinetics determine mammalian siRNA sub-cellu
High-pressure TEM sections were prepared from young adult animals exposed to control RNAi and nhr-31 RNAi. Images are sorted from sections showing the highest EC diameter to the lowest. For ER abundan