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Crystal structure of human insulin degrading enzyme (IDE) in complex with compound 71290

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4re9
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Crystal structure of human insulin degrading enzyme (IDE) in complex with compound 71290 Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide, ... Authors: Liang, W.G, Deprez, R, Deprez, B, Tang, W.J. Deposit date: 2014-09-22 Release date: 2015-09-30 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.908 Å) Cite: Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice. Nat Commun, 6, 2015
创建时间:
2014-09-22
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