Inward-open structure of human glycine transporter 2 in substrate-free state

Inward-open structure of human glycine transporter 2 in substrate-free state Descriptor: CHLORIDE ION, CHOLESTEROL, Sodium- and chloride-dependent glycine transporter 2 Authors: Cantwell Chater, R.P, Peiser-Oliver, J, Pati, T.K, Quinn, A.S, Lotsaris, I, Frangos, Z.J, Anderson, K.E, Tischer, A.E, Williams-Noonan, B.J, Aubrey, K.R, O Mara, M.L, Michaelides, M, Mohammadi, S.A, Cioffi, C.L, Vandenberg, R.J, Shahsavar, A. Deposit date: 2024-12-22 Release date: 2026-02-25 Last modified: 2026-04-08 Method: ELECTRON MICROSCOPY (2.97 Å) Cite: A reversible allosteric inhibitor of GlyT2 for neuropathic pain without on-target side effects. Nat Commun, 17, 2026