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Tables S1 and S2 showing a database of human testis-specific genes and properties relevant to the control of their expression (Note: related publication is a preprint and is published prior to peer review)

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The dataset consists of two <b>.docx</b> files: <b>Table S1.docx</b> and <b>Table S2.docx.</b><b>Table S1.docx </b>shows a database of 239 human testis-specific genes. The table<b> </b>consists of eight columns with eight different parameters. These are:-<b>Index</b>: Includes numbers 1 to 239, corresponding to a total of 239 genes expressed specifically in the human testis.-<b>Gene</b>: This column provides names of the human testis-specific genes.-<b>Chr</b>: Chromosome number where the human testis-specific gene is located. -<b>Exp<sup>a</sup></b>: Exp<sup>RPKM</sup>: Expression in Reads per Kilobase of transcript per Million mapped reads, a measure of transcript expression level for the specified gene.-<b>CGI<sup>b</sup></b>: Indicates the presence of a CpG island within the promoter region of the specified gene. A CpG island is a short stretch of DNA with a higher frequency of the CG sequence than other regions.-<b>Promoter</b>: Indicates the presence or absence of a promoter region within a specified gene.-<b>IG<sup>c</sup></b>: Indicates genes lacking intron sequences (intronless genes).-<b>Testis cell type</b>: Cell type in the human testis, in which the specified gene is expressed in.<br><b>Table S2.docx </b>shows a database of human testis-specific genes that contain a promoter and a transcription factor binding site near the transcription start site. The table<b> </b>consists of 5 columns with 5 different parameters. These are:-<b>Index</b>: A number (from 1 to 239) corresponding to a specific gene. -<b>Gene</b>: This column provides names of the human testis-specific genes.-<b>Chr</b>: Chromosome number where the human testis-specific gene is located. -<b>TF(s) at Transcription Start Site: </b>Name of transcription factor or transcription factors at the transcription start site, followed by the genomic coordinates of the transcription factor binding site.-<b>Nucleotide Sequence: </b>Nucleotide (DNA) sequence of the transcription factor binding site. <br>This work describes the results of other studies that were carried out to examine genes expressed specifically in the human testis, with the aim of creating a gene set representative of all testis-specific genes.<br>The database of human testis-specific genes shown in Table S1, contains a total of 239 genes. Each of these genes was annotated to be highly specific for testis in both the UCSU Genome Browser (version hg38, 2013 [https://genome.ucsc.edu/] and the NCBI gene reference [https://www.ncbi.nlm.nih.gov/].The properties of the 239 human testis-specific genes were examined. These included: the presence of a gene promoter sequence, the presence of a CpG island within the promoter, the presence of a transcription factor binding site near the transcription start site of a promoter and the level of gene expression. Genes lacking introns (intronless genes) as well as testis-specific genes expressed in distinct cell types (eg. spermatocytes, spermatids and spermatogonia) were also identified.<b><br></b><b><br></b><br><b><i></i><sub></sub><sup></sup><i></i><sub></sub><sup></sup><br></b><b><br></b><b><br></b><b><br></b><b><br></b><br>
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figshare
创建时间:
2019-04-12
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