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Crystal structure of PDE5A complexed with its inhibitor

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Protein Data Bank Japan2024-03-20 更新2026-03-21 收录
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Crystal structure of PDE5A complexed with its inhibitor Descriptor: 2-{5-[(4-methylpiperazin-1-yl)sulfonyl]-2-propoxyphenyl}-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... Authors: Ren, J, Chen, T.T, Xu, Y.C. Deposit date: 2012-07-13 Release date: 2013-06-26 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Design, synthesis, and pharmacological evaluation of monocyclic pyrimidinones as novel inhibitors of PDE5. J.Med.Chem., 55, 2012

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2012-07-13
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