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Hypoxia-Inducible Factor (HIF) Prolyl Hydroxylase 2 (PHD2) in Complex with the Carboxamide Analog JNJ43058171

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Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6nmq
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Hypoxia-Inducible Factor (HIF) Prolyl Hydroxylase 2 (PHD2) in Complex with the Carboxamide Analog JNJ43058171 Descriptor: Egl nine homolog 1, FE (II) ION, N-(4-oxo-1,4-dihydrocinnoline-3-carbonyl)glycine Authors: Bembenek, S.D, Mirzadegan, T. Deposit date: 2019-01-11 Release date: 2019-04-24 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Beyond Traditional Structure-Based Drug Design: The Role of Iron Complexation, Strain, and Water in the Binding of Inhibitors for Hypoxia-Inducible Factor Prolyl Hydroxylase 2. Acs Omega, 4, 2019
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2019-01-11
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