Mtb barcoding helps quantify the effect of antibiotic treatment on reinfection establishment and dissemination in Non-human primates

Prior infection with Mycobacterium tuberculosis (Mtb) protects against reinfection. Here, we used barcoded Mtb Erdman libraries to quantify the effect of a standard 4-drug antibiotic treatment prior to re-infection on bacterial establishment and dissemination in non-human primates (Macaca fascicularis).