SNP association in CNV regions.

The SNPs located within the eighteen autosomal CNV regions have previously been evaluated for association with endometriosis (Albertsen et al.), where they failed to pass the genome-wide significance threshold (p<5×10−8) applied in GWA studies. Using the less stringent criteria applied to candidate genes, we found that both regions have 7 non-LD SNPs (r2<0.2) which provide an adjusted significance threshold of 0.007. The two SNPs listed here have genotypic p-Values that are significant at this threshold. Both SNPs were in Hardy-Weinberg equilibrium (p>10−3).