MNGCs: multinucleated giant cells. * rare MNGCs. Objective scoring: Five regions within the H&E section of frontal cortex were examined and scored at 10× magnification using the following criteria for
*Antigen expression counts in the negative control animals are considered false positive counts due to the incapacity of the program to determine artifact staining.
Aβ42 deposition, −: none, +: diffuse deposition in the cerebral cortex,++: diffuse deposition in the cerebral cortex and hippocampus,+++: additional speckled deposits. NFT, −: none, +:a few AT8-positi