Supplementary Material for "Repurposing drugs as inhibitors of BFT-3 toxin, a virulence factor of the gut opportunistic pathogen Bacteroides fragilis, in the animal infection model Galleria mellonella"
收藏资源简介:
This dataset contains raw and processed data related to the study on allosteric inhibition of Bacteroides fragilis toxin isoform 3 (BFT-3). The work explores the repurposing of FDA-approved compounds as anti-virulence agents against enterotoxigenic B. fragilis (ETBF). The data include: • In vitro bacterial growth inhibition assays • Galleria mellonella larval survival curves • Toxicity assessments • Synergy tests with conventional antibiotics The dataset supports the results of the publication:“Repurposing drugs as inhibitors of BFT-3 toxin, a virulence factor of the gut opportunistic pathogen Bacteroides fragilis, in the animal infection model Galleria mellonella”. The file Virulence data.xlsx contains multiple sheets corresponding to experimental results, and a README file is provided for guidance on data content and structure. All data are provided in .xlsx format and can be reused under the selected license.



