Additional file 4 of Testing for causality between systematically identified risk factors and glioma: a Mendelian randomization study

Additional file 4 Additional file, Table 1: Details of instrumented risk factors found from the systematic search of the literature. Additional file, Table 2: Power calculations for each instrumented risk factor. Additional file, Table 3: 25 studies from which the 36 risk factors were evidenced. Additional file, Table 4: Detailed results from sensitivity analyses for each association that met at least the suggestive P value threshold in the IVW analysis. “NA” means there were not enough instruments to conduct this test. “r2” for the Steiger test indicates variance explained and “direction” is given: true, if effect is from exposure to outcome; false, if the effect is from outcome to exposure. Additional file, Table 5: Polygenic Risk Score results for each risk factor and all glioma. Additional file, Table 6: Polygenic Risk Scores for risk factors and glioblastoma. Additional file, Table 7: Polygenic Risk Score results for risk factors and non-glioblastoma (low-grade glioma).