Optimization used in in the publication scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data

OptimizationResults contain the expanded input model for each data set, in the C field are the indices of the core reactions in the expanded input model used to build the multi-cell population for the 121 different parameters, A contains the indices of reaction in the multi-cell population model for the 121 runs, thresh the parameter setting for the cover and REI. The REI is given in %. So 5 REI means 0.05. While A might change because of alternative optimals when run on a different computer, C and the expanded Input model will remain unchanged. Multi_cell_population_CRC and Multi_cell_population_NM are the models obtained by scFASTCORMICS with the optimal setting for Dataset1 and Dataset2, respectively. Please, check the publication (scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data) for more details.