Identification of a forkhead box protein transcriptional network induced in human neutrophils in response to inflammatory stimuli

We performed the first RNAseq analysis of human primary neutrophils exposed to lipopolysaccharide which revealed a robustly enhanced transcriptional network driven by forkhead box (FOX) transcription factors. Comparative gene expression profiling anaysis of RNAseq data for primary human neutrophils treated with vehicle or 1µg/ml LPS for 6 hours. Differential analysis was conducted using edgeR.