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RNA-seq analysis of AML cells in response to ASLAN003

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE128950
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We aim to gain insight into the changes of gene expression induced by ASLAN003, a novel, potent Dihydroorotate Dehydrogenase (DHODH) Inhibitor AML cell lines KG-1 and MOLM-14 cells treated with DMSO and ASLAN003 for 96 hours. Each treatment was triplicated. RNA was extracted and RNA-seq libraries were constructed by TruSeq Library Prep Kit and subjected to Illumina Hiseq4000 deep sequencing (paired-end reads of 100 bases).
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2021-03-01
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