scRNA-seq reveals aging-related immune cell types and regulators in vaginal wall from elderly women with pelvic organ prolapse

raw data of single-cell RNA sequencing of three groups were obtained. Postmenopausal participants with Pelvic Organ Prolapse Quantification (POP-Q) stage III in the anterior compartment were divided into the following groups according to age: <60 years (Young POP), >60 years (Old POP). Postmenopausal participant undergoing excision of vaginal cyst and without prolapse were enrolled as control group (age<60 years). Cells from anterior vaginal wall tissue were obtained for single-cell RNA sequencing.