A fatal bacteremia caused by hypervirulent KPC-2 producing extensively drug-resistant K64-ST11 Klebsiella pneumoniae in Brazil

We reported a fatal bacteremia caused by Klebsiella pneumoniae in a 67-year-old male patient from Brazil. The genomic analysis of three isolates (from blood culture, nasal and anal swabs) showed that the bacteremia was caused by a KPC-2 producing extensively drug-resistant K64-ST11 K. pneumoniae harboring several virulence and antimicrobial resistance genes. This report highlights the clinical implication of genotypic resistance detection in carbapenemase-producing Enterobacteriaceae.