Effects of ginkgetin on liver fibrosis by bulk RNA Sequencing II. Effects of ginkgetin on liver fibrosis by bulk RNA Sequencing II

Ginkgetin could significantly attenuate liver fibrosis in a rat model induced by TAA, including inhibiting hepatic inflammtion and fibrosis. In addition, the related signaling pathways and gene expression were also downregulated by ginkgetin by bulk RNA Sequencing analysis. Overall design: To investigate the effect of ginkgetin on liver fibrosis and the underlying mechanism, we performed bulk RNA Sequencing on the liver tissues from fibrotic rats treated with vehicle (control group) or ginkgetin (10mg/kg/day) (ginkgetin group).