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The circadian clock components BMAL1 and REV-ERB? regulate flavivirus replication. The circadian clock components BMAL1 and REV-ERB? regulate flavivirus replication

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NIAID Data Ecosystem2026-03-10 收录
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We investigated the effect of the REV-ERB agonists on human hepatocytes. Since SR9009 showed the highest anti-viral activity and has been extensively studied in vivo we performed a whole genome microarray on SR9009 (20 µM) treated Huh-7 cells Overall design: Two-condition experiment, Ctrl. vs. SR9009 treatment. Biological replicates: 3 control replicates, 3 treatment replicates.

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2018-12-12
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