Pre-surgical (neoadjuvant) immune checkpoint blockade has shown promising activity in multiple cancer types, but the molecular mechanisms are not well understood. Here, we characterized early kinetic
GP66:I-A b+ spleen T cells were sorted from LCMV infected animals either 7 or 21 days after Clone 13 infection, conditions referred to as Early and Late Chronic. In addition, similar populat
(A) Sorting strategy used to isolate CD11c+CD11blo and CD11c+CD11bhi DCs, CD11c−Ly6Cint neutrophils (Neut) and CD11c−Ly6Chi monocytes (Mono) from skin 5 days after HSV-1 infection. (B,C) Analysis of I
Supplemental table 6 for article titled "T-cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals" by Naranbhai and Nathan et al. CD8+ T cell epitopes in the SA
Interleukin 6 (IL-6) is a pleiotropic cytokine with diverse roles in homeostasis, inflammation, and cancer. Here we performed transcriptional profiling of OT-I CD8+ T cells activated in the presence o
