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Study design for a randomised, blinded, vaccination-challenge study.

NIAID Data Ecosystem2026-03-10 收录

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https://figshare.com/articles/dataset/Study_design_for_a_randomised_blinded_vaccination-challenge_study_/7529513 数据链接链接失效反馈

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Study design for a randomised, blinded, vaccination-challenge study.

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创建时间：

2018-12-28

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敏感性分析

The use of simulation-based sensitivity analyses is fundamental for evaluating and comparing candidate designs of future clinical trials. In this context, sensitivity analyses are especially useful to

DataCite Commons2024-06-09 更新120

Treatment Selection at Interim Analysis Based on a Correlated Early Endpoint in Adaptive Two-Stage Trials with a Primary Endpoint Based on Count Data

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统计

Adaptive two-stage design with treatment selection, also called seamless Phase II/III design, has been recognized to save sample size and time to enhance the development of effective treatments. These

Taylor & Francis Group2025-07-29 更新40

Sample size calculations for superiority trials.

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样本量计算

Efficacy in the reference arm from 60–80%, delta 10–30%, alpha error 0.05, power 80–95%.

Figshare2015-12-02 更新30

Statistical operating characteristics of current early phase dose finding designs with toxicity and efficacy in oncology

肿瘤学

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Traditional phase I dose finding cancer clinical trial designs aim to determine the maximum tolerated dose (MTD) of the investigational cytotoxic agent based on a single toxicity outcome, assuming a m

DataCite Commons2026-04-20 更新100

Randomized non-inferiority trial involving 45-year-old women attending breast cancer screening

乳腺癌筛查

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Breast cancer screening is effective in reducing mortality from the disease. However, the sensitivity of mammography is not optimal, which limits the effectiveness of screening, particularly in younge

Zenodo2025-03-17 更新30

Study design for a randomised, blinded, vaccination-challenge study.

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