FarmGTEx TWAS-server

The FarmGTEx TWAS-Server is the first comprehensive online platform specifically designed for transcriptome-wide association studies (TWAS) in farm animals, integrating extensive eQTL data across humans, cattle, and pigs. It provides a range of advanced functionalities, including gene expression prediction, GWAS summary data imputation, TWAS analysis, cross-species homologous gene comparisons, data visualization, and functional gene annotation. Equipped with powerful tools such as MetaXcan, FUSION, and UTMOST, the platform provides researchers with a seamless, user-friendly interface to support comprehensive multi-omic analyses and drive enhanced research outcomes.FarmGTEx TWAS-Server 是首个专为畜禽转录组全基因组关联研究（transcriptome-wide association studies, TWAS）打造的综合性在线平台，整合了人类、牛与猪的海量表达数量性状位点（expression quantitative trait loci, eQTL）数据。该平台具备多项高级功能，涵盖基因表达预测、全基因组关联研究（Genome-Wide Association Study, GWAS）汇总数据插补、TWAS分析、跨物种同源基因比对、数据可视化以及功能基因注释。平台搭载MetaXcan、FUSION与UTMOST等强大工具，并为研究者提供了流畅易用的交互界面，可支撑全面的多组学分析，助力提升研究成果质量。

搜集汇总

背景与挑战

背景概述

FarmGTEx TWAS-Server是首个专为农场动物设计的全转录组关联研究在线平台，整合了人类、牛和猪的eQTL数据。它提供基因表达预测、GWAS数据填补、TWAS分析和跨物种比较等功能，支持多组学研究和数据可视化。