Hypoxia impairs decitabine-induced expression of HLA-DR in acute myeloid leukaemia cell lines

NIAID Data Ecosystem2026-05-02 收录

急性髓系白血病表观遗传

肿瘤微环境免疫

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE285258 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2025-08-02

Single cell RNA sequence analysis of murine alveolar macrophages in the presence of lung cancer cells. Single cell RNA sequence analysis of murine alveolar macrophages in the presence of lung cancer cells

单细胞RNA测序

肿瘤微环境免疫

To classify the cell population of lung alveolar macrophages in the presence (or absence) of lung cancer cells in vivo, single cell RNA sequence analysis was performed using orthotopic tumor bearing a

NIAID Data Ecosystem80

Table_10_The Prognostic Value of a Tumor Microenvironment-Based Immune Cell Infiltration Score Model in Colon Cancer.xlsx

结直肠癌预后预测

肿瘤微环境免疫

The current study aimed to construct a prognostic predictive model based on tumor microenvironment. CIBERSORT and ESTIMATE algorithms were used to reveal the immune cell infiltration (ICI) landscape o

NIAID Data Ecosystem50

Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion

急性髓系白血病表观遗传

NUP98-PHD融合蛋白机制

The dysregulation of plant homeodomain (PHD) fingers has been implicated in several human diseases, including cancer. In a subset of aggressive acute myeloid leukemia (AML), chromosomal translocations

NIAID Data Ecosystem50

Mediator kinase inhibition further activates super-enhancer-associated genes in AML

急性髓系白血病表观遗传

增强子靶向治疗

Super-enhancers (SEs), which are composed of large clusters of enhancers densely loaded with the Mediator complex, transcription factors and chromatin regulators, drive high expression of genes implic

NIAID Data Ecosystem80

Supplementary Table 7 from Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia

急性髓系白血病表观遗传

超级增强子与药物靶点分析

GO Analysis from Regions of Differential MOLM13 H3K27Ac CUT&Tag (6 Hours After Drug Treatment) Pileup at Enhancers and Promoters

NIAID Data Ecosystem50