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Multicomponent Cascade Synthesis of Trifluoroethyl Isoquinolines from Alkynes and Vinyl Azides

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NIAID Data Ecosystem2026-03-09 收录
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https://figshare.com/articles/dataset/Multicomponent_Cascade_Synthesis_of_Trifluoroethyl_Isoquinolines_from_Alkynes_and_Vinyl_Azides/2092588
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资源简介:
A multicomponent cascade reaction is described that provides concise access to the trifluoroethyl isoquinolines using a Rh­(III)–Cu­(II) bimetallic system and readily available Togni’s reagent. The system tolerates various vinyl azides and internal alkynes. Experimental results suggest that Togni’s reagent might act as a CF3 radical supplier.
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2016-02-12
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