Multicomponent Cascade Synthesis of Trifluoroethyl Isoquinolines from Alkynes and Vinyl Azides
收藏NIAID Data Ecosystem2026-03-09 收录
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A multicomponent cascade reaction is described that provides concise access to the trifluoroethyl isoquinolines using a Rh(III)–Cu(II) bimetallic system and readily available Togni’s reagent. The system tolerates various vinyl azides and internal alkynes. Experimental results suggest that Togni’s reagent might act as a CF3 radical supplier.
创建时间：
2016-02-12
