Limitations and Options for Targeted Therapy of Anaplastic Thyroid Cancer: a Novel genome-based Approach. Supplementary
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https://figshare.com/articles/dataset/Limitations_and_Options_for_Targeted_Therapy_of_Anaplastic_Thyroid_Cancer_a_Novel_genome-based_Approach_Supplementary/14937117/1
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In order to find new therapeutic options in anaplastic thyroid cancer, all FDA-approved drugs for any cancer therapy were identified by searching the databases of National Cancer Institute and MyCancerGenome. Finally, 129 FDA/EMA-approved drugs targeting cancer genetic alterations were included. These drug lists were linked to 128 genes by querying databases of MD Anderson Cancer Center and Drugbank, which encode the potential sites of binding and action. Moreover, special attention was given to specific genetic alterations resulting in either drug sensitivity or drug resistance of targeted therapy. Hereby the expert-crowdsourced, publication-based databases from MyCancerGenome, CIViC, TARGET and OncoKB were mined. <br>
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figshare
创建时间：
2021-07-09
