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Transcriptomics profiles of patient-matched normal kidney and ccRCC pairs

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE102101
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VHL loss is the most common genetic alteration event in ccRCC, but its effect on epigenetic landscape has not been elucidated previously. We describe the genome-wide cis-regulatory landscapes of VHL-deficient ccRCC tumors by comparing the epigenetic changes in terms of histone modifications (H3K27ac, H3K4me1, H3K4me3) with the transcriptomics profiles in 10 pairs of normal kidney and ccRCC tissues. RNA-seq profiles of 10 patient-matched normal kidney and ccRCC pairs
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2021-07-25
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