Effect of T cell supernatants or cytokines on synovial fibroblasts
收藏NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE202367
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To investigate the effects of soluble factors produced by synovial CD8 T cells, we stimulated human rheumatoid arthritis (RA) synovial fibroblasts with supernatants from synovial fluid CD8 T cells, blood CD8 T cells, or synovial fluid CD4 T cells stimulated with anti-CD3/CD28 antibody-coated beads. For comparison, we stimulated RA synovial fibroblasts with recombinant TNF or interferon-gamma or T cell supernatants pre-incubated with TNF-blocking antibodies. Comparative gene expression profiling analysis of RNA-seq data for rheumatoid arthritis synovial fibroblasts treated with supernatants from stimulated CD4 or CD8 T cell populations or with recombinant cytokines ***Please note that FASTQ files will be uploaded to dbGaP since these are human patient samples****
创建时间：
2022-08-11
