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Lactobacillus casei Thymidylate Synthase in Ternary Complex with dUMP and the Phtalimidic Derivative 20C

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Protein Data Bank Japan2023-11-01 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3ik1
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Lactobacillus casei Thymidylate Synthase in Ternary Complex with dUMP and the Phtalimidic Derivative 20C Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-hydroxy-4-(4-methyl-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzoic acid, Thymidylate synthase Authors: Pozzi, C, Cancian, L, Leone, R, Luciani, R, Ferrari, S, Mangani, S, Costi, M.P. Deposit date: 2009-08-05 Release date: 2010-08-11 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Identification of the binding modes of N-phenylphthalimides inhibiting bacterial thymidylate synthase through X-ray crystallography screening J.Med.Chem., 54, 2011
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2009-08-05
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