Genome-wide maps of chromatin state(ATAC-seq) and gene expression(RNA-seq) of cold exposed Dot1L-ablated mouse brown adipose tissue

Using high throughput sequencing we report chromatin accessibility(ATAC-seq) and transcriptome profiling (RNA-seq)and in mouse brown adipose tissue (BAT) upon cold exposure in wildtype and Dot1L-BAT specific KO mice. Identification of genomic chromatin accessibility change profiling and gene expression induced by loss of Dot1L in mouse brown adipose tissue