Patient characteristics.

*1Two patients were from Lao PDR.
*2History of any underlying chronic medical condition documented in the medical notes.
*3Immunosuppression from chemotherapy (n = 4), untreated leukaemia (n = 1), HIV (n = 3, none of whom were on anti-retroviral therapy or any prophylactic antibiotics) or immunosuppressive medication including prednisolone >30 mg/day for >1 week (n = 4; one of these additionally on chemotherapy).
*4Denominator is number of sites (n = 73) since some patients had >1 site of infection.
*5Intravenous catheters (central n = 3, peripheral n = 2, umbilical n = 1), pacemakers (n = 3) and arteriovenous graft (n = 1).
*6Vegetations on transthoracic echocardiography (n = 7); or strong clinical evidence in intravenous drug user (n = 1).
*7Following mitral valve replacement (n = 3), or coronary artery bypass graft (n = 1).
*8Empyema (n = 2), septic emboli to the lungs (n = 1), lung abscesses (n = 1).
*9Liver (n = 2), spleen (n = 1).