Expression profiles of microRNAs in oxidized low-density lipoprotein-stimulated RAW 264.7 cells

Foam cells were one of the hallmarks of atherosclerosis, and microRNAs (miRNAs) played an important role in the formation of foam cells. In order to explore the roles of miRNA in the formation of foam cells, In the present study, to understand the molecular mechanisms of miRNAs involved in AS, we provide insights into the genome-wide dynamic profiles of miRNAs by using high-throughput sequencing technology. Overall design: we investigated miRNA expression profiles from the control group (control-1, control-2, and control-3, n=3) and ox-48h group (ox-48h-1, ox-48h-2 and ox-48h-3, n=3) by using high-throughput sequencing technology.