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Nasal treatment with PLP:OVA-pσ1 after EAE induction<sup>a</sup> reduce inflammatory cell infiltration<sup>b</sup> into the spinal cords.

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aSJL/J mice were challenged s.c. with 200 µg PLP139–151 in complete Freund's adjuvant plus 200 ng PT i.p. on days 0 and 2. bResults are shown in percentage of MHC class II+ CD45high cells from the total cells in spinal cords analyzed by FACS. *, P<0.001 **, P<0.05 for PBS vs. PLP:OVA-pσ1-treated mice. cMice were nasally treatment 6 days post-challenge with 100 µg of PLP:OVA-pσ1 or with PBS.

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2010-01-14
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