Additional file 2 of Alternative 3′ UTR polyadenylation is disrupted in the rNLS8 mouse model of ALS/FTLD
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Supplementary Material 2: Additional file 2. Table S1. APAlyzer analysis of rNLS8 mice. Table S2. REPAC analysis of rNLS8 mice. Table S3. APAlyzer analysis of TDP-43ΔNLS mice. Table S4. REPAC analysis of TDP-43ΔNLS mice. Table S5. DAVID analysis of APA genes in rNLS8 mice. Table S6. APAlyzer analysis of mice targeted with TDP-43 ASOs. Table S7. REPAC analysis mice targeted with TDP-43 ASOs. Table S8. CLIP-seq analysis of mouse TDP-43 binding sites. Table S9. APAlyzer analysis of TDP-43 Tg mice. Table S10. REPAC analysis of TDP-43 Tg mice. Table S11. APAlyzer analysis of microglia from rNLS8 mice. Table S12. REPAC analysis of microglia from rNLS8 mice. Table S13. Gene expression of APA genes in rNLS8 mice. Table S14. Protein levels of APA genes from a proteomic database. Table S15. APAlyzer analysis of TDP-43(M337V) iPSC motor neurons. Table S16. REPAC analysis of TDP-43(M337V) iPSC motor neurons. Table S17. APAlyzer analysis of TDP-43(K263E) iPSC cortical neurons. Table S18. REPAC analysis of TDP-43(K263E) iPSC cortical neurons. Table S19. APAlyzer analysis of TDP-43 RNAi knock-down in human motor neurons. Table S20. REPAC analysis of TDP-43 RNAi knock-down in human motor neurons. Table S21. A comparison of APA genes identified by APAlyzer in rNLS8 mice with list of APA genes in iNeurons from 3′-end sequencing. Table S22. A list of APA genes identified by APAlyzer in rNLS8 mice with evidence of conservation in human disease models. Table S23. A table summarizing the methodological details and results for each set of RNA sequencing data utilized
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2025-01-15



