Data from: Stem cell differentiation trajectories in Hydra resolved at single-cell resolution
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https://datadryad.org/dataset/doi:10.5061/dryad.v5r6077
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资源简介：
The adult Hydra polyp continually renews all of its cells using three
separate stem cell populations, but the genetic pathways enabling this
homeostatic tissue maintenance are not well understood. We sequenced
24,985 Hydra single-cell transcriptomes and identified the molecular
signatures of a broad spectrum of cell states, from stem cells to
terminally differentiated cells. We constructed differentiation
trajectories for each cell lineage and identified gene modules and
putative regulators expressed along these trajectories, thus creating a
comprehensive molecular map of all developmental lineages in the adult
animal. In addition, we built a gene expression map of the Hydra nervous
system. Our work constitutes a resource for addressing questions regarding
the evolution of metazoan developmental processes and nervous system
function.
提供机构：
Dryad
创建时间：
2019-07-24
