PELI1 Selectively Targets Kinase-Active RIP3 for Ubiquitylation-Dependent Proteasomal Degradation

Mendeley Data2018-06-11 更新2026-04-09 收录

泛素蛋白酶体

激酶信号调控

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Original data set for Manuscript (MOLECULAR-CELL-D-17-02035R1)

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2018-06-11

DNA-Dependent Protein Kinase Is a Context Dependent Regulator of Lmx1a and Midbrain Specification

神经元分化

激酶信号调控

The identification of small molecules capable of directing pluripotent cell differentiation towards specific lineages is highly desirable to both reduce cost, and increase efficiency. Within neural pr

NIAID Data Ecosystem80

Discovery of Small Molecule Antagonists of the USP5 Zinc Finger Ubiquitin-Binding Domain

USP5小分子拮抗剂

泛素蛋白酶体

USP5 disassembles unanchored polyubiquitin chains to recycle free monoubiquitin, and is one of the 12 ubiquitin specific proteases featuring a zinc finger ubiquitin-binding domain (ZnF-UBD). This dist

NIAID Data Ecosystem50

Production of Infectious Dengue Virus in Aedes aegypti Is Dependent on the Ubiquitin Proteasome Pathway

登革热病毒机制

泛素蛋白酶体

Dengue virus (DENV) relies on host factors to complete its life cycle in its mosquito host for subsequent transmission to humans. DENV first establishes infection in the midgut of Aedes aegypti and sp

NIAID Data Ecosystem30

Effect of enforced expression of ZAP70 in development of naÃ¯ve B-cell repertoire

B细胞受体库分析

激酶信号调控

We investigate the effect of altered kinase levels (ZAP70) in the VDJ usage of B-cell receptors in humanized mice Overall design: Human cord blood derived CD34+ progenitor cells were transduced with a

NIAID Data Ecosystem60

Cdc42/Rac1-Mediated Activation Primes PAK2 for Superactivation by Tyrosine Phosphorylation

激酶信号调控

磷酸化机制

The involvement of p21-activated kinases (PAKs) in important cellular processes such as regulation of the actin skeleton morphology, transduction of signals controlling gene expression, and execution

PubMed Central30

PELI1 Selectively Targets Kinase-Active RIP3 for Ubiquitylation-Dependent Proteasomal Degradation

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