A DEVELOPMENTAL SYSTEMS BIOLOGY APPROACH TO DEFINE THE MOLECULAR FRAMEWORK OF THE HEMATOPOIETIC STEM CELL NICHE

ChEBI2014-03-01 更新2026-07-21 收录

造血干细胞微环境

发育系统生物学

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-44181 数据链接链接失效反馈

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A DEVELOPMENTAL SYSTEMS BIOLOGY APPROACH TO DEFINE THE MOLECULAR FRAMEWORK OF THE HEMATOPOIETIC STEM CELL NICHE

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2014-03-01

Early B Cell Factor 2 Regulates Hematopoietic Stem Cell Homeostasis in a Cell-Nonautonomous Manner. Mus musculus

造血干细胞微环境

转录因子调控

Hematopoiesis requires the interaction of hematopoietic stem cells (HSCs) with various stromal microenvironments. Here, we examine the role of early B cell factor 2 (Ebf2), a transcription factor expr

NIAID Data Ecosystem80

Gene expression profile of murine bone marrow endosteal populations (2). Mus musculus

造血干细胞微环境

滑膜与骨膜细胞基因表达

A subset of osteoblasts functions as a key component of the hematopoietic stem cell niche. But it is still unclear that the precise cellular and molecular contribution of endosteal cell populations on

NIAID Data Ecosystem40

Molecular analysis of the subaortic hematopoietic stem cell niche [E12.5]. Molecular analysis of the subaortic hematopoietic stem cell niche [E12.5]

造血干细胞微环境

胚胎发育基因表达

Hematopoietic stem cells (HSCs) are formed in the Aorta-Gonad-Mesobephros (AGM) region of mouse midgestation embryos. This process is tightly regulated in time and space by surrounding cells inculding

NIAID Data Ecosystem20

Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture [bulk RNA-seq]. Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture [bulk RNA-seq]

造血干细胞微环境

空间转录组学

The hematopoietic stem cell (HSC) niche has been extensively studied in bone marrow, yet a more systematic investigation into the microenvironment regulation of hematopoiesis in fetal liver is necessa

NIAID Data Ecosystem40

Cyclin A1 regulates the interactions between mouse haematopoietic stem and progenitor cells and their niches

造血干细胞微环境

细胞周期调控

It remains poorly understood how the haematopoietic stem/progenitor cells (HSPC) are attracted to their niches and the functional consequences of such interaction. In the present study, we show that t

Taylor & Francis Group2024-02-28 更新30

A DEVELOPMENTAL SYSTEMS BIOLOGY APPROACH TO DEFINE THE MOLECULAR FRAMEWORK OF THE HEMATOPOIETIC STEM CELL NICHE

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