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Crystal structure of EGFR 696-1022 L858R in complex with CO-1686

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Crystal structure of EGFR 696-1022 L858R in complex with CO-1686 Descriptor: Epidermal growth factor receptor, N-[3-[[2-[[4-(4-ethanoylpiperazin-1-yl)-2-methoxy-phenyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide Authors: Yan, X.E, Zhu, S.J, Yun, C.H. Deposit date: 2017-03-28 Release date: 2017-12-13 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural basis of mutant-selectivity and drug-resistance related to CO-1686. Oncotarget, 8, 2017

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2017-03-28
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