We report a single-cell multi-omics atlas of GBM longitudinal specimens that represents decades of biobanking. We identify novel cell-intrinsic and cell-extrinsic targets for therapy development which
The data includes NGS data analyses from CRISPR-Cas9 knockout screens for 47 human cancer cell lines, performed with PoolQ (v2.2.0). This output includes raw read counts of sgRNAs and corresponding qu
The predicted target genes of differentially expressed miRNAs. The target genes of up-regulated miRNAs (A) and the target genes of down-regulated miRNAs (B) in the comparison ET/CK. (ODS 27 kb)
Angiogenesis and vasculogenic mimicry (VM) are thought to be the predominant processes ensuring tumor blood supply during the growth and metastasis of glioblastoma (GBM). Celastrol has potential anti-
