Small molecule binding data for protein Cyclin-dependent kinase 2, Glycogen synthase kinase-3, JAK3/JAK1, Lysyl-tRNA synthetase, MAP kinase ERK2, Mitogen-activated protein kinase 10, Mitogen-activated

Mendeley Data2024-03-27 更新120

BindingDB Entry 50018934: Synthesis and biological evaluation of coumarin derivatives as selective CYP2A6 inhibitors.

药物先导化合物

CYP51抑制剂

Small molecule binding data for protein Cytochrome P450 2A6 and Cytochrome P450 3A4, Uniprot P08684 and P11509

DataCite Commons2024-04-26 更新50

BindingDB Entry 50018799: Medicinal chemistry strategies targeting PRMT5 for cancer therapy.

癌症靶向治疗

甲基转移酶抑制剂

Small molecule binding data for protein Histone-arginine methyltransferase CARM1, Protein arginine N-methyltransferase 1, and Protein arginine N-methyltransferase 5, Uniprot O14744, Q86X55, and Q99873

DataCite Commons2024-04-26 更新30

BindingDB Entry 50045023: Synthesis and evaluation of C2-carbon-linked heterocyclic-5-hydroxy-6-oxo-dihydropyrimidine-4-carboxamides as HIV-1 integrase inhibitors.

HIV-1整合酶抑制剂

抗病毒药物发现

Small molecule binding data for protein Integrase

DataCite Commons2024-10-23 更新70

BindingDB Entry 50018324: Identification of Natural Products Inhibiting SARS-CoV-2 by Targeting Viral Proteases: A Combined in Silico and in Vitro Approach.

抗病毒药物

病毒蛋白酶抑制剂

Small molecule binding data for protein Replicase polyprotein 1ab, Uniprot P0DTD1

DataCite Commons2024-04-26 更新40