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Structure−Activity Relationship Studies of Illudins: Analogues Possessing a Spiro-cyclobutane Ring

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NIAID Data Ecosystem2026-03-06 收录
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Bicyclic and tricyclic analogues of anticancer sesquiterpene illudin S have been synthesized. These contain a spiro-cyclobutane instead of spiro-cyclopropane structure. The cytotoxicity of the former is less than that of the corresponding cyclopropane-containing compounds.

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2016-05-07
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