Chronic obstructive pulmonary disease (COPD) is a known risk factor for developing lung cancer suggesting that the COPD stroma contains factors supporting tumorigenesis. Since cancer initiation is com
Bronchial epithelial basal cells express high levels of SNAI2 and in order to identify the genes downstream of SNAI2, we performed a knockdown approach with shRNA specific of SNAI2 We used microarrays
This study delved into the interplay between CD244 and Src Homology 2 Domain Containing Phosphatase-2 (SHP2) in chronic obstructive pulmonary disease (COPD) pathogenesis, focusing on apoptosis and inf