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Exome mutations in mouse LMP1 Lymphomas

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE136073
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10 LMP1 expressing mouse lymphomas were sorted and sequenced for exome mutations 10 Rag2KOcgKO were reconstituted with fetal liver hematopoietic stem and progenitor cells (HSPC) from Cd3eKO Cd19-Cre R26LMP1stopf mice. Developing LMP1-driven B-cell lymphomas were transplanted in secondary Rag2KOcgKO or Rag2KO mice. Secondary lymphomas were FACSpurified (CD19+huCD2+). gDNA of sorted lymphoma samples was analyzed by exmoe sequencing
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2020-08-30
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